Endocrine Abstracts

Introduction: Myxoid adrenocortical adenoma was described by Brown et al. in 2000 (1). Myxoid adrenal cortical adenoma with pseudo glandular structure is a particular histological variant and is extremely rare. Accurate diagnosis is based on the combined evaluation of clinical features, adrenal imaging, and pathological features. Immunohistochemical studies (cytokeratin, melan-A, USP10, chromogranin, vimentin) can distinguish adrenocortical adenoma from other retroperitoneal m...

Background: Diabetic foot infections are an important cause of morbidity and mortality associated with poor glycemic control, polyneuropathy and micro/macrovascular diseases. The clinical, laboratory, radiological, pharmacological and/or surgical evaluation is required. We report a case of diabetic foot infection with bilaterally charcot joint.Case: A 52-year-old female patient with type 2 diabetes mellitus (DM), hypertension (HT), coronary artery diseas...

Introduction: Today, approximately 33% of the world population is either overweight or obese. National Health and Nutrition Examination Survey (NHANES) results show that, when 20 years and older American adults are examined, it is seen that 33% of them are overweight, 35.7% of them are obese, and 6.3% of them are morbidly obese (1). Roux-en-Y gastric bypass is a restrictive and malabsorptive combined method and is a complicated operation. Cases of endogenous hyperinsulinemic h...

Introduction: Amyloid goiter is a rare entity caused by massive amyloid infiltration of the thyroid gland. In some cases, differential diagnosis can be challenging. In this report, we present a patient with amyloid goiter caused by secondary amyloidosis.Case: A 48-year-old male patient was admitted to our hospital with the complaints of neck swelling, pain, and mild dysphagia that started three weeks after the SARS-Cov-2 infection and continued for one m...

Introduction: Metastasis to the thyroid gland is a rare clinical presentation. The most common sites of primary tumors that metastasize to the thyroid gland are kidney, lung, gastrointestinal system and breast. Primary gynaecological tumors are account for only 3% of secondary thyroid malignancies. Here, we present a case of thyroid metastasis from squamous cell carcinoma (SCC) of the cervix.Case: A 54-year-old female was consulted to our clinic with the...

Introduction: Surgical removal of the tumor is the primary treatment modality for insulinomas. However, in some patients, surgery is not possible. Octreotide, a somatostatin analogue, is known to suppress insulin secretion. However, there are little data on the use of octreotide in the treatment of insulinoma. Here, we present an insulinoma patient with severe clinical findings and successful control of hypoglycemia after long-acting octreotide.Case: A 7...

Objectives: Preoperative imaging studies are being commonly used in primary hyperparathyroid patients to increase cure rate and to decrease complication rate of surgery. In this study we correlated the surgical outcomes with localization studies performed by various radiologists.Method: A total of 174 patients with primary hyperparathyroidism in which healing of hypercalcemia achieved by parathyroidectomy were evaluated retrospectively. Since our hospita...

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder most commonly characterized by osteolytic bone lesions. Central nervous system (CNS) involvement observed at 6% and Diabetes insipidus (DI) one of the important signs of CNS involvement.A 40-years-old woman presented with polyuria, polydipsia and headache. Water deprivation test was compatible with DI. Magnetic resonance imaging (MRI) shows 4×4 mm focal thickening at the distal infun...

Introduction: Langerhans cell histiocytosis (LCH) is a rare sporadic disease characterized by histiocytic neoplastic infiltration of various organ systems and a wide spectrum of clinical manifestations, ranging from benign and self-limiting to lethal.Case report: We report a rare case of adult onset multi-systemic LCH in a 36-year-old male patient with an initial perianal presentation and incidental finding of subsequent thyroid gland involvement in the ...

Introduction: Serum IGF1 levels declined particularly with hyperglycemia in diabetic patients and lower IGF1 levels has been suggested to be associated with the development of diabetes. IGF1 levels appear to increase with the improvement in glycemic control in diabetic patients but do not reach normal levels. Also, it affected by gender; in this study we aimed to investigate effects of gender on IGF1 changes with basal insulin analogs.Methods: The serum ...